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Full Time Python AI Jobs in San Francisco, California, United States

Browse 161 AI jobs in San Francisco for Oct 2026 with roles open at Cohere, OpenAI, and Formation Bio paying $60K to $500K/year. Work as a Applied AI Architect, Retail, Software Engineer, Security, and Senior Site Reliability Engineer.

Python is required in 17% of Software Engineer jobs postings — the most common role requiring this skill.

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Account Manager Airflow Ansible Cypress Elasticsearch Ethernet JAX LlamaIndex ML Engineer Marketing Lead MongoDB NCCL OpenTelemetry Python RDMA React Recruiter Research Engineer Rust SEO SwiftUI Tableau TensorRT-LLM Triton TypeScript iOS Engineer

Cities

San Francisco New York 123 London 73 Seattle 51

Countries

United States 752 California 288 New York 130 India 106 United Kingdom 97 Canada 83 Texas 64 Washington 62

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Remote Full Time Contract Internship

O

Applied AI Architect, Retail

OpenAI / San Francisco, United States / Hybrid / Staff

Python JavaScript Distributed Systems

29D

Frequently asked questions

What is the average salary for Full Time Python jobs?

161 active listings have salaries ranging from $60K to $500K/year.

Which companies are hiring for Full Time Python jobs?

Top companies hiring include Cohere, OpenAI, and Formation Bio.

Are there remote Full Time Python jobs?

Yes, 18 of 161 are remote.